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The pharmacological actions of 3-4-dihydroxyphenyl-α-methylalanine (α-methyldopa), an inhibitor of 5-hydroxytryptophan decarboxylase

α-Methyldopa (3,4-dihydroxyphenyl-α-methylalanine) is an inhibitor of 5-hydroxytryptophan decarboxylase which is effective in vitro and in vivo. The inhibition is complex and shows coenzyme reversal. Evidence is presented that it acts by coenzyme inactivation. Its administration to mice reduced brai...

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Detalhes bibliográficos
Autor principal: Smith, S. E.
Formato: Artigo
Idioma:Inglês
Publicado em: 1960
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1481928/
https://ncbi.nlm.nih.gov/pubmed/13832156
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