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The excretion and stability to metabolism of bretylium

Bretylium (o-bromobenzylethyldimethylammonium) is a new type of hypotensive drug. It was estimated in extracts of human urine as the methyl orange complex. From 7 to 45% of a single oral dose was found in human urine within 9 hr. The [(14)C] labelled drug was used to investigate excretion by cats. A...

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Autors principals: Duncombe, W. G., McCoubrey, A.
Format: Artigo
Idioma:Inglês
Publicat: 1960
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1481919/
https://ncbi.nlm.nih.gov/pubmed/13818641
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