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The curative power of 4-(2:6-diaminopyrimidin-4-ylamino)phenylarsine oxide (compound 12,065) in infections of trypanosoma rhodesiense in laboratory animals
The toxicity to laboratory animals of 4-(2:6-diaminopyrimidin-4-ylamino)phenylarsine oxide (compound 12,065), and its ability to cure laboratory infections of Trypanosoma rhodesiense were investigated. The intramuscular LD50 to mice was 22 mg./kg.; rats were more susceptible. Monkeys tolerated two d...
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Autor principal: | |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1958
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1481876/ https://ncbi.nlm.nih.gov/pubmed/13618549 |
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