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The curative power of 4-(2:6-diaminopyrimidin-4-ylamino)phenylarsine oxide (compound 12,065) in infections of trypanosoma rhodesiense in laboratory animals

The toxicity to laboratory animals of 4-(2:6-diaminopyrimidin-4-ylamino)phenylarsine oxide (compound 12,065), and its ability to cure laboratory infections of Trypanosoma rhodesiense were investigated. The intramuscular LD50 to mice was 22 mg./kg.; rats were more susceptible. Monkeys tolerated two d...

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Detalhes bibliográficos
Autor principal: Baker, J. R.
Formato: Artigo
Idioma:Inglês
Publicado em: 1958
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1481876/
https://ncbi.nlm.nih.gov/pubmed/13618549
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