The effect of oligonucleotide microarray data pre-processing on the analysis of patient-cohort studies

BACKGROUND: Intensity values measured by Affymetrix microarrays have to be both normalized, to be able to compare different microarrays by removing non-biological variation, and summarized, generating the final probe set expression values. Various pre-processing techniques, such as dChip, GCRMA, RMA...

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Detalhes bibliográficos
Main Authors: Verhaak, Roel GW, Staal, Frank JT, Valk, Peter JM, Lowenberg, Bob, Reinders, Marcel JT, de Ridder, Dick
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1481623/
https://ncbi.nlm.nih.gov/pubmed/16512908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-105
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