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Role of Ribosome and Translocon Complex during Folding of Influenza Hemagglutinin in the Endoplasmic Reticulum of Living Cells

Protein folding in the living cell begins cotranslationally. To analyze how it is influenced by the ribosome and by the translocon complex during translocation into the endoplasmic reticulum, we expressed a mutant influenza hemagglutinin (a type I membrane glycoprotein) with a C-terminal extension....

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Main Authors: Chen, Wei, Helenius, Ari
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC14808/
https://ncbi.nlm.nih.gov/pubmed/10679029
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