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The Escherichia coli Methyl-Directed Mismatch Repair System Repairs Base Pairs Containing Oxidative Lesions

A major role of the methyl-directed mismatch repair (MMR) system of Escherichia coli is to repair postreplicative errors. In this report, we provide evidence that MMR also acts on oxidized DNA, preventing mutagenesis. When cells deficient in MMR are grown anaerobically, spontaneous mutation frequenc...

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Autori principali: Wyrzykowski, Jennifer, Volkert, Michael R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC148063/
https://ncbi.nlm.nih.gov/pubmed/12591888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.5.1701-1704.2003
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