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Parametric Alignment of Drosophila Genomes

The classic algorithms of Needleman–Wunsch and Smith–Waterman find a maximum a posteriori probability alignment for a pair hidden Markov model (PHMM). To process large genomes that have undergone complex genome rearrangements, almost all existing whole genome alignment methods apply fast heuristics...

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Bibliografische gegevens
Hoofdauteurs: Dewey, Colin N, Huggins, Peter M, Woods, Kevin, Sturmfels, Bernd, Pachter, Lior
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1480539/
https://ncbi.nlm.nih.gov/pubmed/16789815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0020073
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