Cadmium Induces the Expression of Grp78, an Endoplasmic Reticulum Molecular Chaperone, in LLC-PK1 Renal Epithelial Cells

To reveal the effects of cadmium exposure on the endoplasmic reticulum (ER) stress response, we examined the expression and function of 78-kDa glucose-regulated protein (Grp78), an ER-resident molecular chaperone, in LLC-PK1 cells. In cells treated with 10 μM cadmium chloride, Grp78 protein levels i...

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Bibliographic Details
Main Authors: Liu, Fang, Inageda, Kiyoshi, Nishitai, Gen, Matsuoka, Masato
Format: Artigo
Language:Inglês
Published: National Institute of Environmental Health Sciences 2006
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1480533/
https://ncbi.nlm.nih.gov/pubmed/16759985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.8920
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