The Homeodomain Transcription Factor Irx5 Establishes the Mouse Cardiac Ventricular Repolarization Gradient

Rhythmic cardiac contractions depend on the organized propagation of depolarizing and repolarizing wavefronts. Repolarization is spatially heterogeneous and depends largely on gradients of potassium currents. Gradient disruption in heart disease may underlie susceptibility to fatal arrhythmias, but...

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Autors principals: Costantini, Danny L., Arruda, Eric P., Agarwal, Pooja, Kim, Kyoung-Han, Zhu, Yonghong, Zhu, Wei, Lebel, Melanie, Cheng, Chi Wa, Park, Chong Y., Pierce, Stephanie A., Guerchicoff, Alejandra, Pollevick, Guido D., Chan, Toby Y., Kabir, M. Golam, Cheng, Shuk Han, Husain, Mansoor, Antzelevitch, Charles, Srivastava, Deepak, Gross, Gil J., Hui, Chi-chung, Backx, Peter H., Bruneau, Benoit G.
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1480411/
https://ncbi.nlm.nih.gov/pubmed/16239150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2005.08.004
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