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Gene and human tumour cell line specific differencesin nitrogen mustard induced DNA alkylation and interstrand crosslinking frequencies.

The levels of N-alkyl purine and DNA interstrand crosslink formation, produced by the clinically used nitrogen mustard antitumour drug mechlorethamine (HN2), were quantitated at the level of specific genes in a panel of human tumour cell lines using modified Southern blotting methods. When purified...

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Udgivet i:Nucleic Acids Res
Principais autores: Sunters, A, Grimaldi, K A, Souhami, R L, Hartley, J A
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1998
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148022/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9837991/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.24.5617
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