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Effects of I Domain Deletion on the Function of the β2 Integrin Lymphocyte Function-associated Antigen-1

A subset of integrin α subunits contain an I domain, which is important for ligand binding. We have deleted the I domain from the β2 integrin lymphocyte function-asssociated antigen-1 (LFA-1) and expressed the resulting non–I domain-containing integrin (ΔI-LFA-1) in an LFA-1-deficient T cell line. Δ...

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Publicado en:Mol Biol Cell
Autores principales: Leitinger, Birgit, Hogg, Nancy
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Cell Biology 2000
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14802/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10679023/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.11.2.677
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