Evolution of antiviral activity in the ribonuclease A gene superfamily: evidence for a specific interaction between eosinophil-derived neurotoxin (EDN/RNase 2) and respiratory syncytial virus.

We have demonstrated that the human eosinophil-derived neurotoxin (EDN, RNase 2), a rapidly evolving secretory protein derived from eosinophilic leukocytes, mediates the ribonucleolytic destruction of extracellular virions of the single-stranded RNA virus respiratory syncytial virus (RSV). While RNa...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Domachowske, J B, Bonville, C A, Dyer, K D, Rosenberg, H F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1998
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147995/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826755/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.23.5327
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