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DSEF-1 is a member of the hnRNP H family of RNA-binding proteins and stimulates pre-mRNA cleavage and polyadenylation in vitro.

DSEF-1 protein selectively binds to a G-rich auxiliary sequence element which influences the efficiency of processing of the SV40 late polyadenylation signal. We have obtained cDNA clones of DSEF-1 using sequence information from tryptic peptides isolated from DSEF-1 protein purified from HeLa cells...

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Bibliographic Details
Main Authors: Bagga, P S, Arhin, G K, Wilusz, J
Format: Artigo
Language:Inglês
Published: 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC147992/
https://ncbi.nlm.nih.gov/pubmed/9826757
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