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Amplification of closed circular DNA in vitro.

The polymerase chain reaction is a powerful technique used to amplify nucleic acids in vitro. The reaction produces linear products, and as of yet, closed circular products have not been possible. Since the replicatively competent form of many DNA molecules is the closed circular form, it would be a...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Chen, Z, Ruffner, D E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147986/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9988636/
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