The life-extending gene Indy encodes an exchanger for Krebs-cycle intermediates

A longevity gene called Indy (for ‘I'm not dead yet’), with similarity to mammalian genes encoding sodium–dicarboxylate cotransporters, was identified in Drosophila melanogaster. Functional studies in Xenopus oocytes showed that INDY mediates the flux of dicarboxylates and citrate across the pl...

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Detalhes bibliográficos
Main Authors: Knauf, Felix, Mohebbi, Nilufar, Teichert, Carsten, Herold, Diana, Rogina, Blanka, Helfand, Stephen, Gollasch, Maik, Luft, Friedrich C., Aronson, Peter S.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Accelerated Publication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479758/
https://ncbi.nlm.nih.gov/pubmed/16608441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060409
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