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X-chromosome targeting and dosage compensation are mediated by distinct domains in MSL-3

In Drosophila, dosage compensation of X-linked genes is achieved by transcriptional upregulation of the male X chromosome. Genetic and biochemical studies have demonstrated that male-specific lethal (MSL) proteins together with roX RNAs regulate this process. Here, we show that MSL-3 is essential fo...

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Bibliografische gegevens
Hoofdauteurs: Buscaino, Alessia, Legube, Gaëlle, Akhtar, Asifa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479548/
https://ncbi.nlm.nih.gov/pubmed/16547465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400658
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