Infection of Human Dendritic Cells with a Mycobacterium tuberculosis sigE Mutant Stimulates Production of High Levels of Interleukin-10 but Low Levels of CXCL10: Impact on the T-Cell Response

The Mycobacterium tuberculosis genome encodes 13 sigma factors. We have previously shown that mutations in some of these transcriptional activators render M. tuberculosis sensitive to various environmental stresses and can attenuate the virulence phenotype. In this work, we focused on extracytoplasm...

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Main Authors: Giacomini, Elena, Sotolongo, Ambar, Iona, Elisabetta, Severa, Martina, Remoli, Maria Elena, Gafa, Valerie, Lande, Roberto, Fattorini, Lanfranco, Smith, Issar, Manganelli, Riccardo, Coccia, Eliana M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479299/
https://ncbi.nlm.nih.gov/pubmed/16714557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01687-05
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