Infection of Human Dendritic Cells with a Mycobacterium tuberculosis sigE Mutant Stimulates Production of High Levels of Interleukin-10 but Low Levels of CXCL10: Impact on the T-Cell Response

The Mycobacterium tuberculosis genome encodes 13 sigma factors. We have previously shown that mutations in some of these transcriptional activators render M. tuberculosis sensitive to various environmental stresses and can attenuate the virulence phenotype. In this work, we focused on extracytoplasm...

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Bibliografiske detaljer
Main Authors: Giacomini, Elena, Sotolongo, Ambar, Iona, Elisabetta, Severa, Martina, Remoli, Maria Elena, Gafa, Valerie, Lande, Roberto, Fattorini, Lanfranco, Smith, Issar, Manganelli, Riccardo, Coccia, Eliana M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479299/
https://ncbi.nlm.nih.gov/pubmed/16714557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01687-05
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