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Role of the DNA ligase III zinc finger in polynucleotide binding and ligation.

Mammalian DNA ligase III exists as two distinct isoforms denoted alpha and beta. Both forms possess a motif that is homologous to the putative zinc finger present in poly(ADP-ribose) polymerase. Here, the role of this motif in the binding and ligation of nicked DNA and RNA substrates in vitro has be...

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Detalhes bibliográficos
Main Authors: Taylor, R M, Whitehouse, J, Cappelli, E, Frosina, G, Caldecott, K W
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC147929/
https://ncbi.nlm.nih.gov/pubmed/9776738
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