Topical Application of Escherichia coli-Vectored Vaccine as a Simple Method for Eliciting Protective Immunity

We report here that animals can be protected against lethal infection by Clostridium tetani cells and Bacillus anthracis spores following topical application of intact particles of live or γ-irradiated Escherichia coli vectors overproducing tetanus and anthrax antigens, respectively. Cutaneous γδT c...

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Главные авторы: Zhang, Jianfeng, Shi, Zhongkai, Kong, Fan-kun, Jex, Edward, Huang, Zhigang, Watt, James M., Van Kampen, Kent R., Tang, De-chu C.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2006
Предметы:
Microbial Immunity and Vaccines
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479276/
https://ncbi.nlm.nih.gov/pubmed/16714593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01836-05
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