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Gamma Interferon, Tumor Necrosis Factor Alpha, and Nitric Oxide Synthase 2, Key Elements of Cellular Immunity, Perform Critical Protective Functions during Humoral Defense against Lethal Pulmonary Yersinia pestis Infection

Pulmonary infection by Yersinia pestis causes pneumonic plague, a rapidly progressing and often fatal disease. To aid the development of safe and effective pneumonic plague vaccines, we are deciphering mechanisms used by the immune system to protect against lethal pulmonary Y. pestis infection. In m...

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Bibliografiske detaljer
Main Authors: Parent, Michelle A., Wilhelm, Lindsey B., Kummer, Lawrence W., Szaba, Frank M., Mullarky, Isis K., Smiley, Stephen T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479272/
https://ncbi.nlm.nih.gov/pubmed/16714568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00185-06
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