High Frequency of CD4(+) T Cells Specific for the TB10.4 Protein Correlates with Protection against Mycobacterium tuberculosis Infection

TB10.4 is a newly identified antigen of Mycobacterium tuberculosis recognized by human and murine T cells upon mycobacterial infection. Here, we show that immunization with Mycobacterium bovis BCG induces a strong, genetically controlled, Th1 immune response against TB10.4 in mice. BALB/c and C57BL/...

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Bibliographic Details
Main Authors: Hervas-Stubbs, Sandra, Majlessi, Laleh, Simsova, Marcela, Morova, Jana, Rojas, Marie-Jesus, Nouzé, Clémence, Brodin, Priscille, Sebo, Peter, Leclerc, Claude
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479244/
https://ncbi.nlm.nih.gov/pubmed/16714570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02086-05
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