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High Levels of Interleukin-10 Impair Resistance to Pulmonary Coccidioidomycosis in Mice in Part through Control of Nitric Oxide Synthase 2 Expression

We have shown previously that there is a direct correlation between IL-10 levels and susceptibility to Coccidioides immitis peritonitis in C57BL/6 (B6), DBA/2, and BXD recombinant inbred mice. We now show that B6 mice are also more susceptible to C. immitis pneumonia and that interleukin-10 (IL-10)-...

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Detalhes bibliográficos
Main Authors: Jimenez, Maria del Pilar, Walls, Lorraine, Fierer, Joshua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479230/
https://ncbi.nlm.nih.gov/pubmed/16714569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01985-05
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