Impact of Human Immunodeficiency Virus Type 1 Subtype C on Drug Resistance Mutations in Patients from Botswana Failing a Nelfinavir-Containing Regimen

Among 16 human immunodeficiency virus-infected (subtype C) Batswana patients who failed nelfinavir (NFV)-containing regimens, the most prevalent mutation observed was D30N (54%), followed by L90M (31%). L89I, K20T/I, and E35D polymorphic changes were also identified. These findings suggest that subt...

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Bibliographische Detailangaben
Hauptverfasser: Doualla-Bell, Florence, Avalos, Ava, Gaolathe, Tendani, Mine, Madisa, Gaseitsiwe, Simani, Ndwapi, Ndwapi, Novitsky, Vladimir A., Brenner, Bluma, Oliveira, Maureen, Moisi, Daniella, Moffat, Howard, Thior, Ibou, Essex, Max, Wainberg, Mark A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479146/
https://ncbi.nlm.nih.gov/pubmed/16723586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01447-05
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