Functional, Biophysical, and Structural Bases for Antibacterial Activity of Tigecycline

Tigecycline is a novel glycylcycline antibiotic that possesses broad-spectrum activity against many clinically relevant species of bacterial pathogens. The mechanism of action of tigecycline was delineated using functional, biophysical, and molecular modeling experiments in this study. Functional as...

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Autors principals: Olson, Matthew W., Ruzin, Alexey, Feyfant, Eric, Rush, Thomas S., O'Connell, John, Bradford, Patricia A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Mechanisms of Action: Physiological Effects
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479133/
https://ncbi.nlm.nih.gov/pubmed/16723578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01499-05
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