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Model System To Evaluate the Effect of ampD Mutations on AmpC-Mediated β-Lactam Resistance

Mutations within the structural gene of ampD can lead to AmpC overproduction and increases in β-lactam MICs in organisms with an inducible ampC. However, identification of mutations alone cannot predict the impact that those mutations have on AmpD function. Therefore, a model system was designed to...

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Autors principals: Schmidtke, Amber J., Hanson, Nancy D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479098/
https://ncbi.nlm.nih.gov/pubmed/16723562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01458-05
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