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Functional Elements within the Dynein Microtubule-binding Domain

Dynein interacts with microtubules through an ATP-sensitive linkage mapped to a structurally complex region of the heavy chain following the fourth P-loop motif. Virtually nothing is known regarding how binding affinity is achieved and modulated during ATP hydrolysis. We have performed a detailed di...

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Detalhes bibliográficos
Main Authors: Koonce, Michael P., Tikhonenko, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC14790/
https://ncbi.nlm.nih.gov/pubmed/10679011
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