Molecular and biochemical characterization of new X-ray-sensitive hamster cell mutants defective in Ku80.
Ku, a heterodimer of approximately 70 and approximately 80 kDa subunits, is a nuclear protein that binds to double-stranded DNA ends and is a component of the DNA-dependent protein kinase (DNA-PK). Cell lines defective in Ku80 belong to group XRCC5 of ionizing radiation-sensitive mutants. Five new i...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1998
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147872/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9742232/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.19.4332 |
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