Molecular and biochemical characterization of new X-ray-sensitive hamster cell mutants defective in Ku80.

Ku, a heterodimer of approximately 70 and approximately 80 kDa subunits, is a nuclear protein that binds to double-stranded DNA ends and is a component of the DNA-dependent protein kinase (DNA-PK). Cell lines defective in Ku80 belong to group XRCC5 of ionizing radiation-sensitive mutants. Five new i...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Errami, A, Finnie, N J, Morolli, B, Jackson, S P, Lohman, P H, Zdzienicka, M Z
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1998
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147872/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9742232/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.19.4332
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