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Purification of plasmids by triplex affinity interaction.

Production of pharmaceutical grade plasmid DNA is an important issue in gene therapy. We developed a method for affinity purification of plasmids by triple helix interaction. This method is based on sequence-specific binding of an oligonucleotide immobilized on a large pore chromatography support to...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Schluep, T, Cooney, C L
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147853/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9742258/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.19.4524
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