Intracellular metabolism of a 2'-O-methyl-stabilized ribozyme after uptake by DOTAP transfection or asfree ribozyme. A study by capillary electrophoresis.

The uptake and cellular metabolism of a fluorescein-labelled synthetic ribozyme stabilized by 2'- O -methyl modification and a 3' inverted thymidine have been studied, employing capillary gel electrophoresis as a novel and efficient analytical method. After internalization by DOTAP transfe...

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Detalhes bibliográficos
Main Authors: Prasmickaite, L, Hogset, A, Maelandsmo, G, Berg, K, Goodchild, J, Perkins, T, Fodstad, O, Hovig, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC147842/
https://ncbi.nlm.nih.gov/pubmed/9722645
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