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A rapid and sensitive method to measure the enzymatic activity of ribosome-inactivating proteins.

A method is described in which the adenosine- N -glycosidase activity of ribosome-inactivating proteins (RIPs) is measured using as substrate a 2251 bp [3H]DNA obtained by PCR amplification of the 731-2981 region of the pBR322 plasmid. The DNA, labelled in the purine ring of adenine, proved a good s...

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Detalhes bibliográficos
Main Authors: Brigotti, M, Barbieri, L, Valbonesi, P, Stirpe, F, Montanaro, L, Sperti, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC147822/
https://ncbi.nlm.nih.gov/pubmed/9722654
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