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Histone H2B mutations in inner region affect ubiquitination, centromere function, silencing and chromosome segregation
The reiterated nature of histone genes has hampered genetic approach to dissect the role of histones in chromatin dynamics. We here report isolation of three temperature-sensitive (ts) Schizosaccharomyces pombe strains, containing amino-acid substitutions in the sole histone H2B gene (htb1(+)). The...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1478186/ https://ncbi.nlm.nih.gov/pubmed/16688222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601110 |
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