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Histone H2B mutations in inner region affect ubiquitination, centromere function, silencing and chromosome segregation

The reiterated nature of histone genes has hampered genetic approach to dissect the role of histones in chromatin dynamics. We here report isolation of three temperature-sensitive (ts) Schizosaccharomyces pombe strains, containing amino-acid substitutions in the sole histone H2B gene (htb1(+)). The...

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Detalhes bibliográficos
Main Authors: Maruyama, Takeshi, Nakamura, Takahiro, Hayashi, Takeshi, Yanagida, Mitsuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1478186/
https://ncbi.nlm.nih.gov/pubmed/16688222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601110
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