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Displacement of D1, HP1 and topoisomerase II from satellite heterochromatin by a specific polyamide

The functions of DNA satellites of centric heterochromatin are difficult to assess with classical molecular biology tools. Using a chemical approach, we demonstrate that synthetic polyamides that specifically target AT-rich satellite repeats of Drosophila melanogaster can be used to study the functi...

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Bibliografiska uppgifter
Huvudupphovsmän: Blattes, Roxane, Monod, Caroline, Susbielle, Guillaume, Cuvier, Olivier, Wu, Jian-hong, Hsieh, Tao-shih, Laemmli, Ulrich K, Käs, Emmanuel
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1478169/
https://ncbi.nlm.nih.gov/pubmed/16675949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601125
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