Automatic detection of conserved RNA structure elements in complete RNA virus genomes.

We propose a new method for detecting conserved RNA secondary structures in a family of related RNA sequences. Our method is based on a combination of thermodynamic structure prediction and phylogenetic comparison. In contrast to purely phylogenetic methods, our algorithm can be used for small data...

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Bibliografiske detaljer
Main Authors: Hofacker, I L, Fekete, M, Flamm, C, Huynen, M A, Rauscher, S, Stolorz, P E, Stadler, P F
Format: Artigo
Sprog:Inglês
Udgivet: 1998
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC147758/
https://ncbi.nlm.nih.gov/pubmed/9685502
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