Chemical display of thymine residues flipped out by DNA methyltransferases.
The DNA cytosine-C5 methyltransferase M. Hha I flips its target base out of the DNA helix during interaction with the substrate sequence GCGC. Binary and ternary complexes between M. Hha I and hemimethylated DNA duplexes were used to examine the suitability of four chemical methods to detect flipped...
Spremljeno u:
| Izdano u: | Nucleic Acids Res |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
1998
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147733/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9671807/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.15.3473 |
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