Efficient modification of a human chromosome by telomere-directed truncation in high homologous recombination-proficient chicken DT40 cells.

Truncation of human chromosomes at desired sites by homologous recombination techniques enables functional and structural analyses of human chromosomes and development of human artificial chromosomes. However, this targeted truncation has been inefficient. We describe here an efficient method for ta...

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發表在:	Nucleic Acids Res
Principais autores:	Kuroiwa, Y, Shinohara, T, Notsu, T, Tomizuka, K, Yoshida, H, Takeda, S, Oshimura, M, Ishida, I
格式:	Artigo
語言:	Inglês
出版:	Oxford University Press 1998
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147703/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9649633/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.14.3447
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