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Synthesis and hybridization analysis of a small library of peptide-oligonucleotide conjugates.

A small library of 49 peptide-oligonucleotide conjugates were synthesized to explore the influence of various peptide side chains on the hybridization properties of the DNA. An invariant 8mer oligonucleotide was coupled to a peptide portion that contained a five residue variable region composed of t...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Harrison, J G, Balasubramanian, S
Format: Artigo
Language:Inglês
Published: Oxford University Press 1998
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147692/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9628910/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.13.3136
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