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Induction of XIST expression from the human active X chromosome in mouse/human somatic cell hybrids by DNA demethylation.

X chromosome inactivation occurs early in mammalian development to transcriptionally silence one of the pair of X chromosomes in females. The XIST RNA, a large untranslated RNA that is expressed solely from the inactive X chromosome, is implicated in the process of inactivation. As previous studies...

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Udgivet i:Nucleic Acids Res
Principais autores: Tinker, A V, Brown, C J
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1998
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147638/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9611238/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.12.2935
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