In vitro and in vivo reconstitution and stability of vertebrate chromosome ends.

Telomeres are essential repetitive sequences at the ends of chromosomes that prevent chromosome fusion and degradation. We have successfully recapitulated these two protective functions in vivo and in vitro by incubating blunt-end DNA constructs having vertebrate telomeric ends in Xenopus eggs and e...

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Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Li, L, Lejnine, S, Makarov, V, Langmore, J P
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 1998
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147635/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9611235/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.12.2908
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