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Triple helices containing arabinonucleotides in the third (Hoogsteen) strand: effects of inverted stereochemistry at the 2'-position of the sugar moiety.

Arabinonucleic acid, the 2'-stereoisomer of RNA, was tested for its ability to recognize double-helical DNA, double-helical RNA and RNA-DNA hybrids. A pyrimidine oligoarabinonucleotide (ANA) was shown to form triple-helical complexes only with duplex DNA and hybrid DNA (Pu):RNA (Py) with an affinity...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Noronha, A, Damha, M J
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147614/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9592152/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.11.2665
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