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DNA sequence analysis by MALDI mass spectrometry.

Conventional DNA sequencing is based on gel electrophoretic separation of the sequencing products. Gel casting and electrophoresis are the time limiting steps, and the gel separation is occasionally imperfect due to aberrant mobility of certain fragments, leading to erroneous sequence determination....

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Kirpekar, F, Nordhoff, E, Larsen, L K, Kristiansen, K, Roepstorff, P, Hillenkamp, F
Format: Artigo
Language:Inglês
Published: Oxford University Press 1998
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147593/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9592136/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.11.2554
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