The (6-4) photoproduct of thymine-thymine induces targeted substitution mutations in mammalian cells.
Two major ultraviolet-induced photolesions of TpT, a (6-4) photoproduct [T(6-4)T] and a cis-syn cyclobutane TT dimer (T=T), were incorporated into a predetermined site of one of the leading and lagging template strands of a double-stranded vector, and the modified DNAs were transfected into simian C...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
1998
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147589/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9592145/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.11.2611 |
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