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An expectation-maximization algorithm for probabilistic reconstructions of full-length isoforms from splice graphs
Reconstructing full-length transcript isoforms from sequence fragments (such as ESTs) is a major interest and challenge for bioinformatic analysis of pre-mRNA alternative splicing. This problem has been formulated as finding traversals across the splice graph, which is a directed acyclic graph (DAG)...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1475746/ https://ncbi.nlm.nih.gov/pubmed/16757580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl396 |
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