Association between cigarette smoking, APC mutations and the risk of developing sporadic colorectal adenomas and carcinomas

BACKGROUND: The association between colorectal cancer (CRC) and smoking has not been consistent. Incomplete smoking history and association to a specific subset of CRC tumors have been proposed as explanations. The adenomatous polyposis coli (APC) gene has been reported to have a "gatekeeper&qu...

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Autors principals: Sæbø, Mona, Skjelbred, Camilla F, Breistein, Rebecca, Lothe, Inger Marie B, Hagen, Per Chr, Bock, Gunter, Hansteen, Inger-Lise, Kure, Elin H
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2006
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1475604/
https://ncbi.nlm.nih.gov/pubmed/16545110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-71
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