Upf1 and Upf2 proteins mediate normal yeast mRNA degradation when translation initiation is limited.
mRNA degradation is coupled with the process of mRNA translation. For example, an mRNA molecule, on which translation is prematurely terminated because of a nonsense codon, may be rapidly degraded. This nonsense-mediated mRNA decay in the yeast Saccharomyces cerevisiae is mediated by the Upf1 and Up...
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| Udgivet i: | Nucleic Acids Res |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1998
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147546/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9580697/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.10.2433 |
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