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Accelerated mRNA decay in conditional mutants of yeast mRNA capping enzyme.

Current models of mRNA decay in yeast posit that 3' deadenylation precedes enzymatic removal of the 5' cap, which then exposes the naked end to 5' exonuclease action. Here, we analyzed gene expression in Saccharomyces cerevisiae cells bearing conditional mutations of Ceg1 (capping enzyme), a 52 kDa...

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Publicat a:Nucleic Acids Res
Autors principals: Schwer, B, Mao, X, Shuman, S
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1998
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147543/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9547258/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.9.2050
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