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Transverse formamide gradients as a simple and easy way to optimise DNA single-strand conformation polymorphism analysis.

Although widely used, the detection of DNA mutations by the single-strand conformation polymorphism (SSCP) method is often hampered by the need to examine a large set of electrophoretic conditions in order to select the one suited to the DNA sequence under study. We show here that the use of transve...

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Publicat a:Nucleic Acids Res
Autors principals: Paccoud, B, Bourguignon, J, Diarra-Mehrpour, M, Martin, J P, Sesboüé, R
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147539/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9547287/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.9.2245
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