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Advantages of 2'-O-methyl oligoribonucleotide probes for detecting RNA targets.

We have compared various kinetic and melting properties of oligoribonucleotide probes containing 2'-O-methylnucleotides or 2'-deoxynucleotides with regard to their use in assays for the detection of nucleic acid targets. 2'-O-Methyl oligoribonucleotide probes bound to RNA targets faster and with muc...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Principais autores: Majlessi, M, Nelson, N C, Becker, M M
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 1998
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147516/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9547284/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.9.2224
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