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The protein splicing domain of the homing endonuclease PI-sceI is responsible for specific DNA binding.

The homing endonuclease PI- Sce I consists of a protein splicing domain (I) and an endonucleolytic domain (II). To characterize the two domains with respect to their contribution to DNA recognition we cloned, purified and characterized the isolated domains. Both domains have no detectable endonucleo...

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Main Authors: Grindl, W, Wende, W, Pingoud, V, Pingoud, A
Formato: Artigo
Idioma:Inglês
Publicado: 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC147489/
https://ncbi.nlm.nih.gov/pubmed/9518476
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