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Cytoplasmic Lipid Droplets Are Sites of Convergence of Proteasomal and Autophagic Degradation of Apolipoprotein B

Lipid esters stored in cytoplasmic lipid droplets (CLDs) of hepatocytes are used to synthesize very low-density lipoproteins (VLDLs), into which apolipoprotein B (ApoB) is integrated cotranslationally. In the present study, by using Huh7 cells, derived from human hepatoma and competent for VLDL secr...

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Detalhes bibliográficos
Main Authors: Ohsaki, Yuki, Cheng, Jinglei, Fujita, Akikazu, Tokumoto, Toshinobu, Fujimoto, Toyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474802/
https://ncbi.nlm.nih.gov/pubmed/16597703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-07-0659
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