Protective role of hydrogen peroxide in oxygen-deprived dopaminergic neurones of the rat substantia nigra

Hydrogen peroxide (H(2)O(2)) is a reactive oxygen species, responsible for cytotoxic damage through the formation of hydroxyl radicals. Dopamine (DA) neurones of the substantia nigra pars compacta (SNc) are highly sensitive to metabolic stress, and they typically respond to energy deprivation with m...

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Bibliographic Details
Main Authors: Geracitano, Raffaella, Tozzi, Alessandro, Berretta, Nicola, Florenzano, Fulvio, Guatteo, Ezia, Viscomi, Maria Teresa, Chiolo, Barbara, Molinari, Marco, Bernardi, Giorgio, Mercuri, Nicola B
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2005
Subjects:
Cell Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474775/
https://ncbi.nlm.nih.gov/pubmed/16002440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.092510
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